Equipment
Search regulatory and administrative support services related to the conduct of research
| Equipment Name | Description |
| Sciex 6500+ with Vanquish Horizon | The 6500+ mass spectrometer is a low-resolution triple quadrupole instrument that provides ultra-low-level quantitation of complex samples. This instrument is used for targeted analysis of small molecules and lipids. |
| Thermo QE HFX with Vanquish Neo | The QE-HFX is a hybrid mass spectrometer that combines a high-resolution, accurate-mass Orbitrap mass analyzer and high-performance quadrupole precursor ion selection making it possible to identify, quantify and confirm analytes of interest in a single analysis. The QE-HFX is utilized for both proteomics and small molecule applications. |
| Thermo IDX with Vanquish Horizon | The ID-X is a high-resolution, MSn-capable, accurate-mass tribrid mass spectrometer for small molecule and lipid identification and characterization. This mass spectrometer is coupled to a Vanquish Horizon UHPLC and is primarily utilized for lipidomic applications. |
| Thermo Exploris 240 with Vanquish Horizon | The Exploris 240 is a high-resolution accurate-mass hybrid instrument that combines a high-performance quadrupole for precursor ion selection with an Orbitrap mass analyzer. This instrument is coupled to a Vanquish Horizon UHPLC and is primarily used for small molecule applications. |
| Bruker TIMSTOF Pro2 with nanoElute 2 | The timsTOF Pro 2 is a high-resolution accurate mass instrument that combines trapped ion mobility (TIMs) with quadrupole and time-of-flight mass analyzers. TIMs and parallel accumulation serial fragmentation (PASEF®) technology provide extremely high MS/MS speed and sensitivity using minimal sample amounts and PASeR real-time database identification. This MS is coupled to a Bruker nanoElute LC and is used for proteomic applications, such as label-free quantitation. |
| Bruker TIMSTOF Ultra2 with EvoSep One | The TIMSTOF Ultra2 is a dedicated instrument for sub-nanogram and single-cell proteomics. It is coupled to an EvoSep One system for rapid semi-automated cleanup and injection of up to 80 unlabeled single cells per calendar day. When employing multiplexed reagents the system can analyze up to 700 single cells per day after suitable inter- and intra-batch quality control and assurance standards. Single-cell isolation and digestion can be performed using a Tecan Uno system for less complex mixtures of dissociated cells. Single cells can also be isolated and pre-processed using our provided protocol for delivery or shipment to the core for analysis. |
| Olink® Signature Q100 | Olink® Signature Q100 is a dedicated system specifically designed for readout of Olink® Target (96 & 48-plex), Olink® Flex (15–21 chosen assays) and Olink® Focus (custom design) protein biomarker panels. Olink® Signature Q100 will measure targeted proteins either quantitatively or relatively using only 1 microliter of plasma or serum. |
Request for Grant Support
Grants
- R level grants that include MSC collaboration require a subcontract covering effort for the MSC co-investigator, supplies, and instrument time based on the scope of work described in the approach. We are happy to assist with preliminary data through our fee for service mechanism and with letters of support, facilities, resources, and other documentation for collaborative grant submissions. Please contact us no later than 45 days in advance for grant submissions and no less than four months in advance if you are seeking preliminary data for your grant submission.
- Pilot grants and small foundation grants will be supported by the MSC and do not necessarily require a sub contract. A budget can be determined for the proposed work and the MSC will support the grant submission with a letter of support and a description of our facilities and resources.
- The faculty of The MSC serve on many thesis committees and mentoring committees for trainees. We are always willing to provide letters of support and grant assistance to trainees and their grant submissions.
- Please contact Stacy Gelhaus, PhD (gstacy@pitt.edu) for questions regarding MSC participation in grant submissions.