- Genetic Engineering in Mice Using CRISPR/Cas9: The ITD Core provides a complete "turnkey" service that includes project design, targeting strategy, synthesis of sgRNA and targeting vectors, assessment of reagent quality and editing efficiency, and mouse genotyping. Dr. Sebastien Gingras consults with investigators on the design of the targeting strategy.
- Classical Transgenesis: The ITD Core assists with the design of transgenic vectors for classical transgenesis projects.
- Genome Engineering in Cell Lines: The ITD Core offers design assistance and consultation for genome engineering projects in cell lines, including custom targeting strategy design, target site identification, targeting vector design, cloning procedure, and genotyping strategy.
- Published Mouse Models: A list of mouse models generated by the ITD Core is available via PubMed.